Simeons' results were not reproduced by other researchers and in 1976 in response to complaints the FDA required Simeons and others to include the following disclaimer on all advertisements:
There is no scientific evidence that HCG is effective in the treatment of obesity. The meta-analysis found insufficient evidence supporting the claims that HCG is effective in altering fat-distribution, hunger reduction or in inducing a feeling of well-being. The authors stated “…the use of HCG should be regarded as an inappropriate therapy for weight reduction…” In the authors opinion, “Pharmacists and physicians should be alert on the use of HCG for Simeons therapy. The results of this meta-analysis support a firm standpoint against this improper indication. Restraints on physicians practicing this therapy can be based on our findings.”
— American Society of Bariatric Physicians' commentary on Lijesen et. al (1995)
There is no real evidence that the hormone injections to lose weight and can be dangerous in some people because it can cause blood clots, depression, and headaches.
The FDA has approved choriogonadotropin hormone injections as a treatment for fertility, but not for weight loss.
According to the American Society of Bariatric Physicians, no new clinical trials have been published since the definitive 1995 meta-analysis.
The scientific consensus is that any weight loss reported by individuals on an "HCG diet" may be attributed entirely to the fact that such diets prescribe calorie intake of between 500 and 1,000 calories per day, substantially below recommended levels for an adult, to the point that this may risk health effects associated with malnutrition.
Popular HGC diets with Human chorionic gonadotropin (hCG) are still available through medical professionals but should be avoided at all cost!
The only dieting programs that work are those that treat weight loss with real food and real food products such as those offered by Ideal Protein.